Perfect
Drugs

Vaccinating
Against

Bioterrorism

Perfect Drugs
Home
Misuse and Abuse of Drugs
Psychotropic Drugs
Before the FDA:
Quack Cures to Medicine Shows
Drug Advertising
Vaccinating Against Bioterrorism

Home
History of Vaccines
How Vaccines Work
Anthrax
Smallpox
Other Biological Agents
Works Cited
Acknowledgements
  History of Vaccines:

In late 18th century England, Dr. Edward Jenner noticed that many cattle workers did not catch smallpox despite repeated exposure the disease. It turned out that all of these people had, at one time, been infected with cowpox--a less lethal bovine form of the disease. Jenner hypothesized that having cowpox created an immunity to smallpox (Grady).

In 1796, Jenner intentionally infected a boy with cowpox. After the boy recovered, Jenner exposed him to smallpox. As he predicted, he did not acquire the disease.

Jenner called this method of smallpox prevention "vaccination," after
"vacca," the Latin word for cow. His vaccine was instantly popular and spread throughout Europe. In 1805, every member of Napoleon's troops were vaccinated. By 1840, vaccination was obligitary in many European countries. Widespread use of the vaccine caused the number of infected people to decline steadily until 1980, when international eradication efforts proved victorious. For the first time in history, humans had defeated a virus. For a more detailed history of smallpox eradication, click here.

Inspired by the success of Jenner, Louis Pasteur developed a live-attenuated vaccine for rabies in 1885. This was the first time a pathogen was altered for therapeutic purposes. Pasteur's biotechnological breakthrough opened the doors to
the field of immunobiology. For instance, von Behring introduced the diphtheria vaccine in 1895 (Grady). Over the course of the following century, three additional types of vaccines were developed, and many vaccines were introduced to prevent a wide range of diseases:

1897 Plague
1923 Diphtheria
1926 Pertussis
1927 Tuberculosis
1927 Tetanus
1935 Yellow Fever
1955 Polio (injectable)
1962 Polio (oral)
1964 Measles
1967 Mumps
1970 Rubella
1981 Hepatitis B

Biomedical Technology Home
Perfect Genes
Perfect Bodies

Joslyn Tobin Bennett
Grinnell College
December 2001